Found. “Dynasty” SC: Quantitative phase imaging of cells and tissues

Popescu 2016

This course aims to help researchers join the exciting and quickly emerging field of biomedical quantitative phase imaging (QPI). In the first part of course I will explain the basic principles of phase contrast microscopy, pros and cons of this method and describe the main approaches of QPI (off-axis, common-path, phase-shifting, and white-light methods). Also, I will talk about processing techniques of QPI data for estimation various cell parameters, such as cell dry mass, red blood cell volume etc.

The second part of the course deals with advances in biomedical applications of QPI. I will review recent published results of applying phase imaging technologies to investigation cell structure and dynamics likewise it clinical applications of tissue studying.

Learning objectives

Intended audience

Scientists and engineers who wish to broaden their research portfolio by exploring the possibilities in the field of quantitative phase imaging. Undergraduate training in optics or equivalent is assumed.

Course Length

3 hours


Gabriel Popescu is an Associate Professor in Electrical and Computer Engineering, University of Illinois at Urbana-Champaign. He received the B.S. and M.S. in Physics from University of Bucharest, in 1995 and 1996, respectively, obtained his M.S. in Optics in 1999 and the Ph.D. in Optics in 2002 from the School of Optics/ CREOL (now the College of Optics and Photonics), University of Central Florida. Dr. Popescu continued his training with the G. R. Harrison Spectroscopy Laboratory at M.I.T., working as a postdoctoral associate. He joined Illinois in August 2007 where he directs the Quantitative Light Imaging Laboratory (QLI Lab) at the Beckman Institute for Advanced Science and Technology. Dr. Popescu is an Associate Editor of Optics Express and Biomedical Optics Express, and Editorial Board Member for Journal of Biomedical Optics and Scientific Reports. He authored a book, edited another book, authored 125 journal publications, gave 350 invited and conference presentations, co-authored 32 patents. He founded Phi Optics, Inc., a start-up company that commercializes quantitative phase imaging technology. He is OSA Fellow and SPIE Fellow.

Personnel to contact with:

Instructor: Prof. Gabriel Popescu