Alexey Ermakov, SSU, Russia
Vitaly Kim, Moscow State University, Russia
Alexey Chumakov, SSU, Russia
Ilya Gorbachev, SSU, Russia
Alexey Savonin, SSU, Russia
Irina Vidyasheva, SSU, Russia
Dmitry Gorin, SSU, Russia
Gennady Khomutov, Moscow State University, Russia
Evgeny Glukhovskoy, SSU, Russia
Methods of remote control over permeability and integrity of microstructures are widely investigated. Such controlled microstructures are applied in sensorics, electronics, etc. Broad group of such control methods are based on the effects of various factors: temperature, acidity, solvent polarity, etc. . To expand the range of possible methods of influence on the shell of microstructures – it's modified by different nanoobjects sensitive to one or the other type of influence [2, 3, 4]. This approach significantly increases the efficiency and perspectives of the use of microcontainers. Due to insertion in the shell of capsules inorganic nanoparticles we have an opportunity to use such methods of group remote opening of microcontainers as ultrasound , magnetic field , microwave electromagnetic radiation centimeter range, [4, 5] etc. However used methods have their restrictions, that leads to the task of researching new alternative methods of group remote control over permeability and integrity of different microstructures and development of new effective functional systems for targeted delivery of substances.
Thereby we investigate alternative methods of such a control. New method of remote group control over permeability and integrity of nanocomposite microstructures of different nature is submitted in this report. Inorganic nanoparticles are used as a sensitizer to an electric field. The destruction possibility of polymeric microcapsules is shown (capsule shell included three layers of marnetite nanoparticles). The destruction possibility of lipid vesicles is shown: living cells covered with nanoparticles of gold are used as vesicles.
The principal way of sensibilization of nanocomposite microstructures to an electric field is investigated in the first time.
The reported study was supported by RFBR, research project No. 11-08-00529-а.
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Mr. Alexey Ermakov
Saratov State University, PhD-student of Nano- And Biomedical Technologies Department
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