Biophysics, Poster

THE IMPACT OF LASER RADIATION ON THE PHOTODISSOCIATION OF CARBOXYHEMOGLOBIN IN BLOOD

S.A. Mamilov, S.S. Esman, D.V. Veligodski, Institute of applied problems of physics and biophysics NAS of Ukraine, 44 Lvivska Str. Kiev, Ukraine
M.M. Asimov, Institute of Physics NAS of Belarus, F. Scaryna Ave. 68, 220072 Minsk, Belarus
E. Borisova, A.I. Gisbrecht, Institute of Electronics, 72 Tzarigradsko Blvd, 1784 Sofia, Bulgaria.

ABSTRACT

We will presents an experimental study of the rate of the carboxyhemoglobin (HbCO) photodissociation in blood under the influence of the transcutaneous laser irrariation in visible spectral range from 405 to 700 nm.
Despite the similarity of the HbCO and HbO2 action spectra, the designed 3-wavelengths measurement system makes it possible to reliability measure the HbCO decrease level.
The results show that there is a relatively narrow spectral range in the visible region where one could effectively (up to 50%) dissociates carboxyhemoglobin in blood through the tissue.
The obtained results can be used in phototherapy in clinical applications for effective treatment of the HbCO poisoning.

ACKNOWLEDGEMENTS: This work is supported, in part, by Bulgarian Science Fund, Grant DNTS-01/0006/2012

Representing author

photo

Dr. Ekaterina Georgieva Borisova

Institute of Electronics, Bulgarian Academy of Sciences, Associate Professor
Sofia, Bulgaria

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