RCW'12, Internet Report

OPTICAL PROPERTIES OF THE HUMAN NASAL POLYPS IN THE SPECTRAL RANGE FROM 300 TO 2500 NM

Ekaterina A. Kolesnikova, Saratov State University, Russia Alia A. Muldasheva, Saratov State Medical University, Russia
Julia P. Ireneva,Saratov State Medical University, Russia Darya N. Zmeeva,Saratov State University, Russia
Alexey N. Bashkatov,Saratov State University, Russia
Elina A. Genina,Saratov State University, Russia
Vyacheslav I. Kochubey,Saratov State University, Russia
Anatoly B. Knyazev,Saratov State Medical University, Russia
Valery V. Tuchin,Saratov State University, Russia;Institute of Precise Mechanics and Control RAS, Saratov, Russia;
University of Oulu, Oulu, Finland

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ABSTRACT

The results of the study of optical properties of the human nasal polyps in the spectral range from 300 to 2500 nm are presented. The experiments were performed with 20 samples of the human nasal polyps, obtained from different patients in the course of elective surgery. The samples were kept in saline at temperature 4-5°C during 48 hours until spectral measurements. The dimensions of the samples were approximately 15×15 mm, the average thickness was 1.0±0.5 mm.
The total and collimated transmittance and total reflectance spectra were measured using the LAMBDA 950 spectrometer (PerkinElmer, UK) with an integrated sphere. The halogen lamp was used as a light source for the NIR and visible measurements and deuterium lamp for UV measurements.
Inverse Monte Carlo technique has been used for processing the experimentally measured spectra of the tissue samples; wavelength dependence of absorption and scattering coefficients, and anisotropy factor has been obtained.
The analysis of the results has shown that investigated spectra are depend on scattering coefficient of collagen fibers and on absorption band of interstitial matrix water. The absorption bands of oxyhemoglobin at the wavelengths 415, 540 and 570 nm are well seen.
Our results can be used for the development of new methods and optimization of the existing ones of therapy of rhinologic diseases.

Representing author

photo

Mrs. Ekaterina Alexandrovna Kolesnikova

Saratov State University, Student
Saratov, Russia

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