Biophotonics, Internet Report

DIMETHYL SULFOXIDE (DMSO) DIFFUSION IN SKIN TISSUE

Marina D. Kozintseva, Saratov State University, Russia
Alexey N. Bashkatov, Saratov State University, Russia
Elina A. Genina, Saratov State University, Russia
Valery V. Tuchin, Saratov State University, Russia

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ABSTRACT

The possibility of selective translucence of the superficial skin layers is very useful in developing functional imaging and therapeutic techniques. A potential benefit of the optical clearing is the improvement of laser therapeutic techniques that enable sufficient light penetration to a target embedded in tissue. Combination of optical clearing with laser radiation can reduce the laser fluences required for a therapeutic effect. However, in spite of numerous investigations deal with transport of DMSO within biological tissue the problem of estimating the diffusion coefficient of the agent in skin has not been studied in details. Goal of the study is to measure the diffusion coefficient of DMSO in skin

Representing author

photo

Dr. Alexey Nikolaevich Bashkatov

Saratov State University, Associate Professor
Saratov, Russia

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