Microscopy, Oral Report

NORMAL AND ABNORMAL FETAL DEVELOPMENT

Kirill V. Larin

Department of Biomedical Engineering, University of Houston, 2028 SERC Building, Houston, TX 77204, USA
Molecular Physiology and Biophysics, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77584, USA
Institute of Optics and Biophotonics, Saratov State University, Saratov, Russia

ABSTRACT

A live high-resolution imaging method for mouse embryos would contribute to high-throughput morphological screening of mouse mutants with different developmental abnormalities. Recently, we have developed methods for live mouse embryonic imaging in static culture at early gestation (E7.5 - E10.5) as well as in utero imaging at later gestation (E12.5 – E18.5) with Optical Coherence Tomography (OCT). In this presentation I’ll overview the capability of OCT for imaging and analysis of mouse embryos with genetically-engineered and environmentally-induced developmental defects of different organ systems.

Representing author

photo

Dr. Georgy Garifovich Akchurin

Saratov State University, Institute of Precision Mechanics and Control, RAS
Saratov, Russia

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