RCW'12, Oral Report

APPLICATION OF CONFOCAL LASER MICROSCOPY FOR MESH EXPLANTS CONTROL

Ivan Bratchenko, Samara State Aerospace University, Russia
Valeriy Zakharov, Samara State Aerospace University, Russia
Vladimir Belokonev, Samara State Medical University, Russia
Hongkui Yi, Samara State Medical University, Russia

ABSTRACT

Usage of different chemical composition tissues substitutes defines life time of implanted explants and gives an opportunity to vary prosthetic material acclimation rate in different tissues. The main aim of this study is analysis of confocal laser microscopy usage in herniology, detection of regularities, which appear in the course of different shape and chemical composition explants splicing with tissues, identifying opportunities of various wound healing pathologies detection, appearing in the explant area.
Significant impact on the relapse probability in hernioplasty provide a state of mesh implants surface and defects in their weaving. Moreover, it is possible qualitative change in the microtrauma with increasing of size, number and density of microdefects – formation of free play area in the encapsulation zone. To eliminate these effects and growth of pathologies preoperative microscopic control of implants should be carried out. Confocal laser microscopy allows one to carry out comprehensive control of mesh explants, determining the presence of weaving heterogeneities in explant. To assess the ability of explant visualization in tissues by optical methods model experiments based on Monte-Carlo technique were carried out. Mathematical simulations showed that postoperative control and monitoring of wound healing process and encapsulation of the implant are possible by the instrumentality of differential backscattering methods with the depth of visualization up to five millimeters.
The developed technique allows comprehensive monitoring of transplant surgery and postoperative control of tissues and explant in encapsulation area. Control of mesh explants microscopic structure allows screening of explant samples that do not meet the requirements for the transplant surgery.
This study was supported by supreme program for 2012-2014 years "Visualization and control of mesh explants encapsulation process".

Representing author

photo

Dr. Ivan Alekseevich Bratchenko

Samara University, Associeate professor
Samara, Russia

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