Biophotonics, Internet Invited Lecture

HUMAN SKIN OPTICAL PROPERTIES MODIFICATIONS UPON OPTICAL CLEARING AGENTS ESTIMATED FROM SPATIALLY-RESOLVED TISSUE OPTICAL SPECTROSCOPY

Prisca Rakotomanga (Université de Lorraine, CNRS, CRAN, France), Grégoire Khairallah (Université de Lorraine, CNRS, Metz-Thionville Regional Hospital, France), Charles Soussen (Université de Lorraine, CNRS, France), Marine Amouroux (Université de Lorraine, CNRS, France), Frédéric Marchal (Université de Lorraine, CNRS, Institut de Cancérologie de Lorraine), Alain Delconte (Université de Lorraine, CNRS), Wei Feng (Huazhong University of Science and Technology, Wuhan, China), Dan Zhu ((Huazhong University of Science and Technology, Wuhan, China), Walter Blondel (Université de Lorraine, CNRS).

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ABSTRACT

Optical clearing agents’ impact on skin optical properties (OP) was investigated using spatially – resolved bimodal spectroscopy and inverse Monte Carlo modelling. Optical spectra were obtained on an original hybrid model made of ex vivo human skin as a top layer and of agarose and porphyrin based – nanoparticles as a bottom layer. First results are given in terms of estimated absorption and scattering coefficients of skin layer before and after OCA application.

Representing author

photo

Dr. Marine AMOUROUX

Université de Lorraine - CRAN
France

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