Brian Pogue, Dartmouth College, United States
Optical tools have been widely used in radiation therapy, for alignment, patient position verification, real time tracking, and dosimetry. While the position verification systems are largely simple alignment with lasers or surface mapping tools, the dosimetry systems utilize scintillation or cherenkov light sensing to track relative or absolute radiation dose. These tools have been advancing to the point where it is now possible to map position and dose in patients for treatment verification, or to complete quality audit studies in high resolution water phantoms prior to therapy. Future innovations will likely be in the combination of non-contact systems for verification and tracking of radiotherapy. Additionally the use of optically active agents for enhancing radiotherapy efficiacy has been expanding and a number of organic molecules and non-organic nanoparticles have shown some level of therapeutic enhancement when administered prior to radiation therapy. These developments will be reviewed, with a focus on the most promising future directions.
Prof. Brian Pogue
Dartmouth College, Professor
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