Biophotonics, Internet Invited Lecture

MONITORING OF THE CEREBRAL STATUS DURING CARDIAC ARREST

Vladislav Toronov, Department of Physics, Ryerson University, Canada
Thu Nguyen, Department of Physics, Ryerson University, Canada
Reyhaneh Nosrati, Department of Physics, Ryerson University, Canada
Steve Lin, Keenan Research Centre, Li Ka Shing Knowledge Institute, St. Michael’s Hospital, Toronto, Canada
Paul Dorian, Keenan Research Centre, Li Ka Shing Knowledge Institute, St. Michael’s Hospital, Toronto, Canada

Discussion Live Chat Presentation (52.94 Mb)

ABSTRACT

A novel hyperspectral near-infrared spectroscopy (hNIRS) technique was developed and evaluated to measure cerebral oxygen delivery and aerobic metabolism in animal models and in patients undergoing the trans-catheter aortic valve implantation operation. Cerebral parameters measured included cerebral tissue hemoglobin concentration, oxygenation, and changes in the cytochrome C oxidase concentration, which was the marker of the intracellular oxygen metabolism. The results showed advantages of direct monitoring of the intracellular oxygen in addition to blood oxygenation. We also proposed a design of a portable NIRS device which can allow for monitoring oxygen metabolism in cardiac arrest patients in field conditions.

Representing author

photo

Prof. Vladislav Toronov

Ryerson University, Associate Professor
Toronto, Canada

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